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AAN 2024 | Comparing the clinical and cognitive characteristics of adult-onset vs late-onset MS

Damiano Mistri, Neuropsychologist, PhD student, IRCCS San Raffaele Scientific Institute, Milan, Italy, shares the details of a study aiming to compare the differences in clinical and cognitive characteristics between late-onset and adult-onset multiple sclerosis (MS). The results of the analysis showed that patients with late-onset MS had more severe physical disability, poorer performance on motor tests, and a higher prevalence of cognitive dysfunction, especially in the areas of memory, attention, and verbal fluency. Interestingly, in both late-onset and adult-onset disease, male patients had more severe clinical and cognitive profiles compared to their female counterparts. This interview took place at the American Academy of Neurology (AAN) Annual Meeting 2024 in Denver, CO.

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