MDS 2023 | Phase II study of risvodetinib in Parkinson’s disease

Milton Werner, PhD, Inhibikase Therapeutics, Inc., Atlanta, GA, discusses the development of risvodetinib, a selective c-Abl kinase inhibitor. Research studies show that administering this inhibitor to animal models of Parkinson’s disease completely reverses the disease progression, even in advanced stages. Notably, their studies also examine the role of the gastrointestinal (GI) tract in Parkinson’s disease, as patients often experience severe GI issues related to the same neural neuron class found in their brains. This unique approach involves analyzing both brain and GI tract outcomes in a systemic manner. The ongoing Phase II trial has already produced promising results, and further studies are underway to confirm the therapeutic potential of risvodetinib. This interview took place at the 2023 International Congress of Parkinson’s Disease and Movement Disorders in Copenhagen, Denmark.

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