ESOC 2025 | The use of perfusion-weighted MRI to predict cerebrovascular events after TIA
Philipp Bücke, MD, MSc, University Hospital Bern, Bern, Switzerland, discusses the use of perfusion-weighted magnetic resonance imaging (MRI) to identify patients at risk of progressing from a transient ischemic attack (TIA). By analyzing perfusion images, doctors may be able to detect tissue at risk, which could indicate a higher likelihood of future stroke and potentially guide more intensive treatment and follow-up care. This approach could lead to more stringent medical therapy and closer monitoring for patients with TIA. This interview took place at the 11th European Stroke Organisation Conference (ESOC) in Helsinki, Finland.
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Transcript
I think it is important from the current TIA definition that we need an MRI in order to be able to distinguish between a TIA and a real ischemic stroke. And in, like, a normal, at least in our institution, in our normal MRI protocol, there is, like, the DWI and there’s the flair and they’re like all the typical MRI parameters and we also do the MR perfusion...
I think it is important from the current TIA definition that we need an MRI in order to be able to distinguish between a TIA and a real ischemic stroke. And in, like, a normal, at least in our institution, in our normal MRI protocol, there is, like, the DWI and there’s the flair and they’re like all the typical MRI parameters and we also do the MR perfusion. And the MR perfusion shows us actually if there is sort of a tissue at risk and this tissue at risk might be in a patient with a TIA where no stroke has yet occurred which might be actually telling us that in the future this tissue might be going to die and this patient will be having a stroke which means that the symptoms that have been there in the TIA will be ongoing and the patient might be disabled or even dead in the future. And so we believe that if we look at those perfusion images, which we haven’t done before and which aren’t done regularly, that we could actually identify patients that are at risk and might be needed for, like, an inpatient treatment or something else just to be more thorough in the workup and more stringent in the medical therapy, for example.
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