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AAN 2023 | The promise of proteomics in sleep medicine

Emmanuel Mignot, MD, PhD, Stanford University School of Medicine, Palo Alto, CA, describes the many applications of proteomics across various fields, including sleep medicine. For example, in the circadian field, the inability to easily measure the phase of the central biological clock is a significant limitation. The development of multivariate protein panels to predict the circadian phase, sleep deprivation (“sleep debt”), or the presence of sleep disorders will significantly impact the diagnosis of sleep disorders in clinical practice. The use of proteomics in the clinic is the future of personalized medicine. This interview took place at the American Academy of Neurology Annual Meeting 2023 in Boston, MA.

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Dr Mignot reports research/clinical trial support as a Stanford investigator or consulting fees from Takeda, Merck, Idorsia, Jazz, Centessa, Merck, Avadel, Apnea Co, Axome, Apple, Harmony Biosciences, and Sunovion.