AAN 2026 | Baseline characteristics to predict response to aerobic training and physical rehabilitation in MS

Tetsu Morozumi, PT, PhD(c), Vita-Salute San Raffaele University, Milan, Italy, comments on the heterogeneity in individual response to physical rehabilitation in people with multiple sclerosis (MS) and the potential of baseline characteristics to predict response to aerobic training and physical rehabilitation. Dr Morozumi highlights that measures of diffusivity were significant predictors of response in both aerobic and non-aerobic groups, suggesting that less severe microstructural white matter damage may enable greater brain plasticity and adaptive changes in response to exercise. This interview took place at the 78th American Academy of Neurology (AAN) Annual Meeting in Chicago, IL.

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