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EAN 2026 | New approaches in the surgical management of tremor syndromes

Antonella Macerollo, MD, PhD, FRCP, FEBN, FEAN, Walton Centre NHS Foundation Trust, Liverpool, United Kingdom, shares insights into promising advances in the surgical management of tremor syndromes. Dr Macerollo highlights local field potentials in deep brain stimulation and brain-targeting with MRI-guided focused ultrasound. This interview took place at the 12th Congress of the European Academy of Neurology (EAN) in Geneva, Switzerland.

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Transcript

I think the most fascinating area of research regarding surgery for tremor syndromes would be the use of for example local field potential in deep brain stimulation surgery for tremor syndrome as we have developed for example for Parkinson disease, which is a way to correlate some neuro physiological biomarker to the outcome of the surgery. And also close the loop of DBS in tremor syndrome. So I found this quite fascinating because we can learn from what has been developed in terms of technology from Parkinson disease...

I think the most fascinating area of research regarding surgery for tremor syndromes would be the use of for example local field potential in deep brain stimulation surgery for tremor syndrome as we have developed for example for Parkinson disease, which is a way to correlate some neuro physiological biomarker to the outcome of the surgery. And also close the loop of DBS in tremor syndrome. So I found this quite fascinating because we can learn from what has been developed in terms of technology from Parkinson disease. Moreover, the MRI-guided focused ultrasound with the emerging target of the brain. I think there are potential to treat for example challenging syndromes like dystonic tremor because we can develop or learn how to target different part of the brain to improve the outcome. I think in the long term radio frequency and gamma knife they will be completely replaced by these two procedures.

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