ISC 2026 | The development of a risk score to identify individuals with migraine who are at high risk of stroke
Souvik Sen, MD, University of South Carolina, Columbia, SC, discusses the development of a risk score to identify individuals with migraine who are at high risk of stroke. Prof. Sen highlights that the score incorporates various factors to predict stroke risk over a 10-20 year period. This interview took place at the 2026 International Stroke Congress (ISC), held in New Orleans, LA.
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Transcript
Yeah, so migraine is quite common, and we’ve been trying to develop a migraine risk score, meaning if somebody has migraine, can we use a score to figure out who has had a stroke and who’s likely to have a stroke and who does not? And this is very important for the young and the middle-aged population who have migraines. And we found there was a certain migraine characteristic, like if they had an aura from migraine, or they had migraine which just started within the last 10 years...
Yeah, so migraine is quite common, and we’ve been trying to develop a migraine risk score, meaning if somebody has migraine, can we use a score to figure out who has had a stroke and who’s likely to have a stroke and who does not? And this is very important for the young and the middle-aged population who have migraines. And we found there was a certain migraine characteristic, like if they had an aura from migraine, or they had migraine which just started within the last 10 years. There was also a lot of stroke risk factors, such as high blood pressure, diabetes, and being older. So those were also added into that mix. And last but not least, we also looked at some findings in the ECG and heart rate variability. And we came up with a risk score, 0 to 24. And then what we found was folks who had a score greater than 5, they had a high risk of stroke over the next 10 to 20 years, actually, two decades.
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